to get all flake8 passing

fixes #3110

when that :class:`.Column` is referred to in an explicit
:class:`.PrimaryKeyConstraint` for that table.  This behavior now
matches that of when the :class:`.Column` itself has the
:paramref:`.Column.primary_key` flag set to ``True``, which is
intended to be an exactly equivalent case.
fixes #3023

Removed ungrammatical apostrophes from documentation, replacing
"it's" with "its" where appropriate (but in a few cases with "it is"
when that read better).

While doing that, I also fixed a couple of minor typos etc.
as I noticed them.

Found using: https://github.com/intgr/topy

specify a :func:`.text` expression as the target; the index no longer
needs to have a table-bound column present if the index is to be
manually added to the table, either via inline declaration or via
:meth:`.Table.append_constraint`. fixes #3028

If autoloading of a table fails, don't register it in a metadata
instance. It seems that the original behaviour was accidentally
changed in f6198d9abf453182f4b111e0579a7a4ef1614e79, restore it.

Closes issue #2988

is currently being supported in addition to nose, and will likely
be preferred to nose going forward.   The nose plugin system used
by SQLAlchemy has been split out so that it works under pytest as
well.  There are no plans to drop support for nose at the moment
and we hope that the test suite itself can continue to remain as
agnostic of testing platform as possible.  See the file
README.unittests.rst for updated information on running tests
with pytest.

The test plugin system has also been enhanced to support running
tests against mutiple database URLs at once, by specifying the ``--db``
and/or ``--dburi`` flags multiple times.  This does not run the entire test
suite for each database, but instead allows test cases that are specific
to certain backends make use of that backend as the test is run.
When using pytest as the test runner, the system will also run
specific test suites multiple times, once for each database, particularly
those tests within the "dialect suite".   The plan is that the enhanced
system will also be used by Alembic, and allow Alembic to run
migration operation tests against multiple backends in one run, including
third-party backends not included within Alembic itself.
Third party dialects and extensions are also encouraged to standardize
on SQLAlchemy's test suite as a basis; see the file README.dialects.rst
for background on building out from SQLAlchemy's test platform.

methods, classes, builtins, functools.partial(), everything known so far
- use get_callable_argspec() within ColumnDefault._maybe_wrap_callable, re: #2979